At age 10, Cataleya Restrepo (Zoe Saldana, Avatar) witnesses the brutal murder of her parents by a Colombian drug lord Don Luis. Cataleya manages to escape the bullets of the assassin and reach Chicago, where her gangster uncle, Emilio, lives. Emilio is doing his best to keep Cataleya out of the criminal life, but she is determined to become a professional killer. At 25, Cataleya has become a real killer operating on behalf of her uncle, but her sole desire is to find Don Luis and avenge the death of her parents.